"Tobacco Road" is a song written and first recorded by John D. Loudermilk in 1960 that was a hit for The Nashville Teens in 1964 and has since become a standard across several musical genres.

Originally framed as a folk song, "Tobacco Road" was a semi-autobiographical tale of growing up in Durham, North Carolina. Released on Columbia Records, it was not a hit for Loudermilk, achieving only minor chart success in Australia. Other artists, however, immediately began recording and performing the song.

The English group The Nashville Teens' garage rock/blues rock rendering was a bold effort featuring prominent piano, electric guitar and bass drum parts and a dual lead vocal. Mickie Most produced it with the same tough-edged-pop feel that he brought to The Animals' hits. "Tobacco Road" was a trans-Atlantic pop hit in 1964, reaching number 6 on the UK singles chart and number 14 on the U.S. singles chart. While the Teens would have some further success in England, in the U.S. "Tobacco Road" became another one-hit wonder of the British Invasion. The Nashville Teens' cover version was featured at the close of episode 1 of season 4, "Public Relations", of the hit television show Mad Men on July 25, 2010.

In the 1970s, songwriters Nicky Chinn and Mike Chapman claimed to have been inspired by "Tobacco Road" while writing Sweet's "Blockbuster", after accusations of stealing the guitar riff from David Bowie's "Jean Genie".

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