Tissue plasminogen activator

PLAT

Protein PLAT PDB 1a5h.png

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
1A5H, 1BDA, 1PK2, 1PML, 1RTF, 1TPG, 1TPK, 1TPM, 1TPN, 5BRR

Identifiers

PLAT, T-PA, TPA, plasminogen activator, tissue type

External IDs

OMIM: 173370 MGI: 97610 HomoloGene: 717 GeneCards: PLAT

Gene ontology
Molecular function	• glycoprotein binding • peptidase activity • phosphoprotein binding • protein binding • serine-type peptidase activity • serine-type endopeptidase activity • receptor binding • hydrolase activity
Cellular component	• cytoplasm • extracellular matrix • apical part of cell • secretory granule • extracellular region • cell surface • extracellular exosome • extracellular space
Biological process	• negative regulation of proteolysis • response to hypoxia • fibrinolysis • blood coagulation • smooth muscle cell migration • proteolysis • cellular protein modification process • platelet-derived growth factor receptor signaling pathway • plasminogen activation
Sources:Amigo / QuickGO

RNA expression pattern

PBB GE PLAT 201860 s at fs.png

More reference expression data

Orthologs

Species

Human

Mouse


5327


18791


ENSG00000104368


ENSMUSG00000031538


P00750


P11214

RefSeq (mRNA)


NM_033011 NM_000930 NM_000931 NM_001319189


NM_008872

RefSeq (protein)


NP_000921 NP_001306118 NP_127509


NP_032898.2 NP_032898

Location (UCSC)

Chr 8: 42.18 – 42.21 Mb

Chr 8: 22.76 – 22.78 Mb

PubMed search

1A5H, 1BDA, 1PK2, 1PML, 1RTF, 1TPG, 1TPK, 1TPM, 1TPN, 5BRR

ENSG00000104368

ENSMUSG00000031538

NM_033011
NM_000930
NM_000931
NM_001319189

NP_000921
NP_001306118
NP_127509

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Wikipedia

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