Tissue factor

F3
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1AHW, 1BOY, 1DAN, 1FAK, 1J9C, 1JPS, 1O5D, 1TFH, 1UJ3, 1W0Y, 1W2K, 1WQV, 1WSS, 1WTG, 1WUN, 1WV7, 1Z6J, 2A2Q, 2AEI, 2AER, 2B7D, 2B8O, 2C4F, 2CEF, 2CEH, 2CEZ, 2CFJ, 2EC9, 2F9B, 2FIR, 2FLB, 2HFT, 2PUQ, 2ZP0, 2ZWL, 2ZZU, 3ELA, 3TH2, 3TH3, 3TH4, 4IBL, 4M7L, 4Z6A, 4ZMA, 4YLQ, 2FLR
Identifiers
Aliases	F3, CD142, TF, TFA, coagulation factor III, tissue factor
External IDs	OMIM: 134390 MGI: 88381 HomoloGene: 1511 GeneCards: F3
Gene ontology Molecular function • protein binding • cytokine receptor activity • phospholipid binding • serine-type endopeptidase activity • protease binding Cellular component • integral component of membrane • membrane • extracellular matrix • intrinsic component of external side of plasma membrane • plasma membrane • extracellular region • extracellular exosome • cell surface • extracellular space • serine-type peptidase complex Biological process • hemostasis • positive regulation of protein kinase B signaling • positive regulation of endothelial cell proliferation • cytokine-mediated signaling pathway • positive regulation of cell migration • activation of blood coagulation via clotting cascade • positive regulation of platelet-derived growth factor receptor signaling pathway • positive regulation of angiogenesis • blood coagulation, extrinsic pathway • activation of plasma proteins involved in acute inflammatory response • activation of cysteine-type endopeptidase activity involved in apoptotic process • positive regulation of positive chemotaxis • blood coagulation • protein processing Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	2152	14066
Ensembl	ENSG00000117525	ENSMUSG00000028128
UniProt	P13726	P20352
RefSeq (mRNA)	NM_001993 NM_001178096	NM_010171
RefSeq (protein)	NP_001171567 NP_001984	NP_034301.3
Location (UCSC)	Chr 1: 94.53 – 94.54 Mb	Chr 3: 121.72 – 121.74 Mb
PubMed search

1AHW, 1BOY, 1DAN, 1FAK, 1J9C, 1JPS, 1O5D, 1TFH, 1UJ3, 1W0Y, 1W2K, 1WQV, 1WSS, 1WTG, 1WUN, 1WV7, 1Z6J, 2A2Q, 2AEI, 2AER, 2B7D, 2B8O, 2C4F, 2CEF, 2CEH, 2CEZ, 2CFJ, 2EC9, 2F9B, 2FIR, 2FLB, 2HFT, 2PUQ, 2ZP0, 2ZWL, 2ZZU, 3ELA, 3TH2, 3TH3, 3TH4, 4IBL, 4M7L, 4Z6A, 4ZMA, 4YLQ, 2FLR

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