Tight junction protein 1

TJP1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2H2B, 2H2C, 2H3M, 2JWE, 2KXR, 2KXS, 2RCZ, 3CYY, 3LH5, 3SHU, 3SHW, 3TSV, 3TSW, 3TSZ, 4OEO, 4OEP, 4Q2Q, 4YYX
Identifiers
Aliases	TJP1, ZO-1, Tight junction protein 1
External IDs	MGI: 98759 HomoloGene: 2445 GeneCards: TJP1
Gene ontology Molecular function • calmodulin binding • protein binding • cadherin binding • protein C-terminus binding • protein domain specific binding • connexin binding Cellular component • membrane • bicellular tight junction • plasma membrane • basolateral plasma membrane • gap junction • apical junction complex • cytosol • cytoplasm • cell-cell adherens junction • apical part of cell • cell junction • nucleus • cell-cell junction • adherens junction • intercalated disc • apical plasma membrane • apicolateral plasma membrane • intercellular canaliculus • occluding junction • protein complex Biological process • establishment of endothelial intestinal barrier • hippo signaling • cell-cell junction assembly • cell-cell signaling involved in cell-cell junction organization • regulation of bicellular tight junction assembly • blastocyst formation • sensory perception of sound • response to lipopolysaccharide • response to drug • negative regulation of vascular permeability • response to ethanol • response to magnetism • cellular response to glucose stimulus Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	7082	21872
Ensembl	ENSG00000277401 ENSG00000104067	ENSMUSG00000030516
UniProt	Q07157	P39447
RefSeq (mRNA)	NM_001301025 NM_001301026 NM_003257 NM_175610 NM_001330239	NM_001163574 NM_009386
RefSeq (protein)	NP_001287954 NP_001287955 NP_001317168 NP_003248 NP_783297 NP_001287954.1 NP_001287955.1	NP_001157046 NP_033412
Location (UCSC)	Chr 15: 29.7 – 29.97 Mb	Chr 7: 65.3 – 65.53 Mb
PubMed search

2H2B, 2H2C, 2H3M, 2JWE, 2KXR, 2KXS, 2RCZ, 3CYY, 3LH5, 3SHU, 3SHW, 3TSV, 3TSW, 3TSZ, 4OEO, 4OEP, 4Q2Q, 4YYX

7082

21872

ENSG00000277401
ENSG00000104067

ENSMUSG00000030516

Q07157

...
Wikipedia