Thrombopoietin

THPO

Protein THPO PDB 1v7m.png

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
1V7M, 1V7N

Identifiers

THPO, MGDF, MKCSF, ML, MPLLG, THCYT1, TPO, thrombopoietin

External IDs

MGI: 101875 HomoloGene: 398 GeneCards: THPO

Gene ontology
Molecular function	• cytokine activity • growth factor activity • hormone activity
Cellular component	• extracellular region • extracellular space
Biological process	• multicellular organism development • positive regulation of hematopoietic stem cell proliferation • myeloid cell differentiation • cell proliferation • positive regulation of megakaryocyte differentiation • thrombopoietin-mediated signaling pathway • positive regulation of protein kinase B signaling • positive regulation of ERK1 and ERK2 cascade • positive regulation of protein phosphorylation
Sources:Amigo / QuickGO

RNA expression pattern

PBB GE THPO 211154 at tn.png

PBB GE THPO 211155 s at tn.png

PBB GE THPO 211831 s at tn.png

More reference expression data

Orthologs

Species

Human

Mouse


7066


21832


ENSG00000090534


ENSMUSG00000022847


P40225


P40226

RefSeq (mRNA)

NM_000460 NM_001177597 NM_001177598 NM_001289997 NM_001289998
NM_001290003 NM_001290022 NM_001290026 NM_001290027 NM_001290028 NM_199228 NM_199356


NM_001173505 NM_009379 NM_001289894 NM_001289896

RefSeq (protein)

NP_000451 NP_001171068 NP_001171069 NP_001276926 NP_001276927
NP_001276932 NP_001276951 NP_001276955 NP_001276956 NP_001276957

NP_001166976.1 NP_001276823.1 NP_033405.1 NP_001166976 NP_001276823
NP_001276825 NP_033405

Location (UCSC)

Chr 3: 184.37 – 184.38 Mb

Chr 16: 20.73 – 20.73 Mb

PubMed search

ENSG00000090534

ENSMUSG00000022847

NM_001290003
NM_001290022
NM_001290026
NM_001290027
NM_001290028
NM_199228
NM_199356

NM_001173505
NM_009379
NM_001289894
NM_001289896

NP_001276932
NP_001276951
NP_001276955
NP_001276956
NP_001276957

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Wikipedia

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