Sir Thomas Vesey, 1st Baronet (1668?–1730), was an Anglo-Irish clergyman. He was Bishop of Ossory from 1714 to 1730.
He was born at Cork, Ireland when his father, John Vesey, was dean of the church there, was educated at Eton and Christ Church, Oxford, and became a fellow of Oriel College. He married Mary, only surviving daughter and heiress of Denny Muschamp, esq., of Horsley, Surrey and his wife Elizabeth Boyle, and, through her coming into a considerable estate. On 13 July (patent 28 Sept.) 1698, he was created a Baronet, of Abbeyleix in the Baronetage of Ireland.
Taking holy orders, he was ordained as a priest on 24 June 1700, and, becoming chaplain to the James Butler, 2nd Duke of Ormonde and Archdeacon of Tuam, was by his influence advanced to the bishopric of Killaloe on 12 June 1713. The following year he became Bishop of Ossory.
He died on 6 Aug. 1730, and was buried in St. Anne's Church, Dublin. His only son and heir, John Vesey, was created Baron Knapton in 1750 and was the ancestor to the Viscounts de Vesci and William Vesey-FitzGerald, 2nd Baron FitzGerald and Vesey. Elizabeth Vesey was his daughter.