Tartrate resistant acid phosphatase

ACP5
Available structures PDB Human UniProt search: PDBe RCSB List of PDB id codes 2BQ8, 1WAR
Identifiers
Aliases	ACP5, HPAP, SPENCDI, TRAP, TRACP5a, TRACP5b, TrATPase, acid phosphatase 5, tartrate resistant
External IDs	OMIM: 171640 HomoloGene: 115578 GeneCards: ACP5
Gene ontology Molecular function • ferric iron binding • acid phosphatase activity • metal ion binding • ferrous iron binding • hydrolase activity Cellular component • integral component of membrane • cytosol • lysosome • extracellular exosome Biological process • riboflavin metabolic process • dephosphorylation Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	54	n/a
Ensembl	ENSG00000102575	n/a
UniProt	P13686	n/a
RefSeq (mRNA)	NM_001111034 NM_001111035 NM_001111036 NM_001611 NM_001322023	n/a
RefSeq (protein)	NP_001104504 NP_001104505 NP_001104506 NP_001308952 NP_001602	n/a
Location (UCSC)	Chr 19: 11.57 – 11.58 Mb	n/a
PubMed search		n/a

2BQ8, 1WAR

54

n/a

ENSG00000102575

n/a

P13686

n/a

NM_001111034
NM_001111035
NM_001111036
NM_001611
NM_001322023

n/a

NP_001104504
NP_001104505
NP_001104506
NP_001308952
NP_001602

n/a

Tartrate-resistant acid phosphatase (TRAP or TRAPase), also called acid phosphatase 5, tartrate resistant (ACP5), is a glycosylated monomeric metalloprotein enzyme expressed in mammals. It has a molecular weight of approximately 35kDa, a basic isoelectric point (7.6-9.5), and optimal activity in acidic conditions. TRAP is synthesized as latent proenzyme and activated by proteolytic cleavage and reduction. It is differentiated from other mammalian acid phosphatases by its resistance to inhibition by tartrate and molecular weight.

...
Wikipedia