TUBG1

TUBG1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1Z5V, 1Z5W, 3CB2
Identifiers
Aliases	TUBG1, CDCBM4, GCP-1, TUBG, TUBGCP1, tubulin gamma 1
External IDs	MGI: 101834 HomoloGene: 833 GeneCards: TUBG1
Gene location (Human) Chr. Chromosome 17 (human) Band 17q21.2 Start 42,609,676 bp End 42,615,234 bp
Gene location (Mouse) Chr. Chromosome 11 (mouse) Band 11 D|11 64.24 cM Start 101,119,938 bp End 101,126,419 bp
Gene ontology Molecular function • nucleotide binding • GTP binding • structural constituent of cytoskeleton • protein binding • GTPase activity • identical protein binding Cellular component • cytoplasm • ciliary basal body • recycling endosome • cytosol • centrosome • pericentriolar material • apical part of cell • gamma-tubulin complex • Butt • microtubule organizing center • condensed nuclear chromosome • spindle microtubule • polar microtubule • cell leading edge • centriole • cytoplasmic microtubule • microtubule • cytoskeleton • non-motile cilium Biological process • meiotic spindle organization • G2/M transition of mitotic cell cycle • cytoplasmic microtubule organization • microtubule-based process • microtubule cytoskeleton organization • microtubule nucleation • ciliary basal body docking • regulation of G2/M transition of mitotic cell cycle Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	7283	103733
Ensembl	ENSG00000131462	ENSMUSG00000035198
UniProt	P23258	P83887
RefSeq (mRNA)	NM_001070	NM_134024
RefSeq (protein)	NP_001061	NP_598785
Location (UCSC)	Chr 17: 42.61 – 42.62 Mb	Chr 17: 101.12 – 101.13 Mb
PubMed search

1Z5V, 1Z5W, 3CB2

7283

103733

ENSG00000131462

ENSMUSG00000035198

P23258

P83887

NM_001070

NM_134024

NP_001061

NP_598785

Tubulin, gamma 1 is a protein in humans that is encoded by the TUBG1 gene. This gene encodes a member of the tubulin superfamily. The encoded protein localizes to the centrosome where it binds to microtubules as part of a complex referred to as the gamma-tubulin ring complex. The protein mediates microtubule nucleation and is required for microtubule formation and progression of the cell cycle.

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