TST (gene)

TST
Identifiers
Aliases	TST, RDS, thiosulfate sulfurtransferase
External IDs	MGI: 98852 HomoloGene: 37759 GeneCards: TST
Gene ontology Molecular function • transferase activity • 5S rRNA binding • thiosulfate sulfurtransferase activity • RNA binding Cellular component • mitochondrial inner membrane • extracellular exosome • mitochondrion • mitochondrial matrix • extracellular space Biological process • rRNA transport • rRNA import into mitochondrion • epithelial cell differentiation • cyanate catabolic process Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	7263	22117
Ensembl	ENSG00000128311	ENSMUSG00000044986
UniProt	Q16762	P52196
RefSeq (mRNA)	NM_003312 NM_001270483	NM_009437
RefSeq (protein)	NP_001257412 NP_003303	NP_033463.1 NP_033463
Location (UCSC)	Chr 22: 37.01 – 37.02 Mb	Chr 15: 78.4 – 78.41 Mb
PubMed search

7263

22117

ENSG00000128311

ENSMUSG00000044986

Q16762

P52196

NM_003312
NM_001270483

NM_009437

NP_001257412
NP_003303

NP_033463.1
NP_033463

Thiosulfate sulfurtransferase is an enzyme that in humans is encoded by the TST gene.

The product of this gene is a mitochondrial matrix enzyme that is encoded by the nucleus. It may play roles in cyanide detoxification, the formation of iron-sulfur proteins, and the modification of sulfur-containing enzymes. The gene product contains two highly conservative domains (rhodanese homology domains), suggesting these domains have a common evolutionary origin.

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Wikipedia