TREX1

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
2IOC, 2O4G, 2O4I, 2OA8, 3B6O, 3B6P, 3MXI, 3MXJ, 3MXM, 3U3Y, 3U6F, 4YNQ

Identifiers

TREX1, AGS1, CRV, DRN3, HERNS, three prime repair exonuclease 1

External IDs

Genetically Related Diseases

Gene ontology
Molecular function	• protein homodimerization activity • metal ion binding • single-stranded DNA binding • exodeoxyribonuclease III activity • MutSalpha complex binding • protein binding • 3'-5' exonuclease activity • 3'-5'-exodeoxyribonuclease activity • MutLalpha complex binding • nucleic acid binding • nuclease activity • exonuclease activity • hydrolase activity
Cellular component	• cytoplasm • cytosol • nuclear envelope • endoplasmic reticulum membrane • membrane • endoplasmic reticulum • nucleus
Biological process	• DNA recombination • DNA metabolic process • regulation of type I interferon production • DNA replication • mismatch repair • DNA repair • nucleic acid phosphodiester bond hydrolysis
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse

Entrez


11277


22040


ENSG00000213689


ENSMUSG00000049734


Q9NSU2


Q91XB0

RefSeq (mRNA)


NM_033629 NM_007248 NM_016381 NM_033627 NM_033628


NM_001012236 NM_011637

RefSeq (protein)


NP_009179 NP_057465 NP_338599


NP_001012236.1 NP_035767.4 NP_001012236 NP_035767

Location (UCSC)

PubMed search