TPM1

Identifiers

TPM1, C15orf13, CMD1Y, CMH3, HTM-alpha, LVNC9, TMSA, HEL-S-265, tropomyosin 1 (alpha)

External IDs

Gene ontology
Molecular function	• cytoskeletal protein binding • structural constituent of cytoskeleton • protein binding • actin binding • structural constituent of muscle • actin filament binding
Cellular component	• cytoplasm • filamentous actin • muscle thin filament tropomyosin • sarcomere • stress fiber • ruffle membrane • myofibril • bleb • cytoskeleton • cytosol • actin filament • actin cytoskeleton
Biological process	• regulation of muscle contraction • movement of cell or subcellular component • muscle contraction • regulation of heart contraction • positive regulation of ATPase activity • cardiac muscle contraction • negative regulation of vascular associated smooth muscle cell migration • negative regulation of vascular smooth muscle cell proliferation • ruffle organization • positive regulation of heart rate by epinephrine • wound healing • in utero embryonic development • cellular response to reactive oxygen species • ventricular cardiac muscle tissue morphogenesis • negative regulation of cell migration • cytoskeleton organization • regulation of cell shape • muscle filament sliding • sarcomere organization • positive regulation of stress fiber assembly • positive regulation of cell adhesion • actin filament organization
Sources:Amigo / QuickGO

RNA expression pattern

More reference expression data

Orthologs

Species

Human

Mouse

Entrez


7168


n/a

Ensembl


ENSG00000140416


n/a

UniProt


P09493


n/a

RefSeq (mRNA)

NM_000366 NM_001018004 NM_001018005 NM_001018006 NM_001018007
NM_001018008 NM_001018020 NM_001301244 NM_001301289 NM_001330344 NM_001330346 NM_001330351


n/a

RefSeq (protein)

NP_000357 NP_001018004 NP_001018005 NP_001018006 NP_001018007
NP_001018008 NP_001018020 NP_001288173 NP_001288218 NP_001317273 NP_001317275 NP_001317280 NP_001018006.1


n/a

Location (UCSC)

Chr 15: 63.04 – 63.07 Mb

n/a

PubMed search

n/a

7168

n/a

ENSG00000140416

n/a

P09493

n/a

NM_001018008
NM_001018020
NM_001301244
NM_001301289
NM_001330344
NM_001330346
NM_001330351

n/a

NP_001018008
NP_001018020
NP_001288173
NP_001288218
NP_001317273
NP_001317275
NP_001317280
NP_001018006.1

n/a

Tropomyosin alpha-1 chain is a protein that in humans is encoded by the TPM1 gene. This gene is a member of the tropomyosin (Tm) family of highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells.

...
Wikipedia