TLR10

TLR10
Available structures PDB Human UniProt search: PDBe RCSB List of PDB id codes 2J67
Identifiers
Aliases	TLR10, CD290, toll like receptor 10
External IDs	OMIM: 606270 HomoloGene: 12809 GeneCards: TLR10
Gene ontology Molecular function • transmembrane signaling receptor activity Cellular component • integral component of membrane • plasma membrane • membrane • integral component of plasma membrane Biological process • toll-like receptor 10 signaling pathway • regulation of cytokine secretion • inflammatory response • positive regulation of inflammatory response • MyD88-dependent toll-like receptor signaling pathway • immune response • signal transduction • immune system process • toll-like receptor signaling pathway • innate immune response Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	81793	n/a
Ensembl	ENSG00000174123	n/a
UniProt	Q9BXR5	n/a
RefSeq (mRNA)	NM_001017388 NM_001195106 NM_001195107 NM_001195108 NM_030956	n/a
RefSeq (protein)	NP_001017388 NP_001182035 NP_001182036 NP_001182037 NP_112218	n/a
Location (UCSC)	Chr 4: 38.77 – 38.78 Mb	n/a
PubMed search		n/a

2J67

81793

n/a

ENSG00000174123

n/a

Q9BXR5

n/a

NM_001017388
NM_001195106
NM_001195107
NM_001195108
NM_030956

n/a

NP_001017388
NP_001182035
NP_001182036
NP_001182037
NP_112218

n/a

Toll-like receptor 10 is a protein that in humans is encoded by the TLR10 gene. TLR10 has also been designated as CD290 (cluster of differentiation 290). TLR10 has not been extensively studies because it is a pseudogene in mice, though all other mammalian species contain an intact copy of the TLR10 gene. Unlike other TLRs, TLR10 does not activate the immune system and has instead been shown to suppress inflammatory signaling on primary human cells. This makes TLR10 unique among the TLR family. No known ligand is currently known for TLR10.

...
Wikipedia