TIMP1

TIMP1

Protein TIMP1 PDB 1d2b.png

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
1D2B, 1OO9, 1UEA, 2J0T, 3MA2, 3V96

Identifiers

TIMP1, CLGI, EPA, EPO, HCI, TIMP, TIMP-1, TIMP metallopeptidase inhibitor 1

External IDs

MGI: 98752 HomoloGene: 36321 GeneCards: TIMP1

Gene ontology
Molecular function	• peptidase inhibitor activity • enzyme inhibitor activity • cytokine activity • metal ion binding • protease binding • protein binding • metalloendopeptidase inhibitor activity • growth factor activity • zinc ion binding
Cellular component	• extracellular matrix • proteinaceous extracellular matrix • extracellular region • basement membrane • extracellular exosome • platelet alpha granule lumen • extracellular space • endoplasmic reticulum lumen • collagen trimer
Biological process	• response to cytokine • negative regulation of peptidase activity • aging • response to peptide hormone • platelet degranulation • wound healing • negative regulation of apoptotic process • extracellular matrix disassembly • negative regulation of trophoblast cell migration • response to organic substance • cell activation • cartilage development • regulation of integrin-mediated signaling pathway • positive regulation of cell proliferation • response to hormone • negative regulation of membrane protein ectodomain proteolysis • negative regulation of endopeptidase activity • negative regulation of catalytic activity • negative regulation of metallopeptidase activity • post-translational protein modification • cellular protein metabolic process
Sources:Amigo / QuickGO

RNA expression pattern

PBB GE TIMP1 201666 at fs.png

More reference expression data

Orthologs

Species

Human

Mouse


7076


21857


ENSG00000102265


ENSMUSG00000001131


P01033 Q6FGX5


P12032

RefSeq (mRNA)


NM_003254


NM_001044384 NM_001294280 NM_011593

RefSeq (protein)


NP_003245 NP_003245.1


NP_001037849 NP_001281209 NP_035723

Location (UCSC)

Chr X: 47.58 – 47.59 Mb

Chr X: 20.87 – 20.87 Mb

PubMed search

1D2B, 1OO9, 1UEA, 2J0T, 3MA2, 3V96

ENSG00000102265

ENSMUSG00000001131

NM_001044384
NM_001294280
NM_011593

NP_003245
NP_003245.1

NP_001037849
NP_001281209
NP_035723

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Wikipedia

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