TIA-1

TIA1 cytotoxic granule-associated RNA binding protein
Identifiers
Symbol	TIA1
Entrez	7072
HUGO	11802
OMIM	603518
RefSeq	NM_022173
UniProt	P31483
Other data
Locus	Chr. 2 p13

TIA1 is a 3'UTR mRNA binding protein and can bind the 5'TOPsequence of 5'TOP mRNAs. It is associated with programmed cell death (apoptosis) and regulates alternative splicing of the gene encoding the Fas receptor, an apoptosis-promoting protein.

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