THEM2

ACOT13
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2F0X, 2H4U, 3F5O
Identifiers
Aliases	ACOT13, PNAS-27, THEM2, HT012, acyl-CoA thioesterase 13
External IDs	MGI: 1914084 HomoloGene: 41273 GeneCards: ACOT13
Gene location (Human) Chr. Chromosome 6 (human) Band 6p22.3 Start 24,667,035 bp End 24,705,065 bp
Gene location (Mouse) Chr. Chromosome 13 (mouse) Band 13|13 A3.1 Start 24,817,948 bp End 24,831,517 bp
Gene ontology Molecular function • hydrolase activity • acyl-CoA hydrolase activity Cellular component • cytosol • spindle • extracellular exosome • cytoskeleton • mitochondrion • nucleus • cytoplasm Biological process • protein homotetramerization • acyl-CoA metabolic process Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	55856	66834
Ensembl	ENSG00000112304	ENSMUSG00000006717
UniProt	Q9NPJ3	Q9CQR4
RefSeq (mRNA)	NM_018473 NM_001160094	NM_025790
RefSeq (protein)	NP_001153566 NP_060943	NP_080066
Location (UCSC)	Chr 6: 24.67 – 24.71 Mb	Chr 6: 24.82 – 24.83 Mb
PubMed search

2F0X, 2H4U, 3F5O

55856

66834

ENSG00000112304

ENSMUSG00000006717

Q9NPJ3

Q9CQR4

NM_018473
NM_001160094

NM_025790

NP_001153566
NP_060943

NP_080066

Acyl-CoA thioesterase 13 is a protein that in humans is encoded by the ACOT13 gene. This gene encodes a member of the thioesterase superfamily. In humans, the protein co-localizes with microtubules and is essential for sustained cell proliferation.

The orthologous mouse protein forms a homotetramer and is associated with . The mouse protein functions as a medium- and long-chain acyl-CoA thioesterase. Multiple transcript variants encoding different isoforms have been found for this gene.

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