TGFα

TGFA

Protein TGFA PDB 1mox.png

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
1GK5, 1MOX, 1YUF, 1YUG, 2TGF, 3E50, 3TGF, 4TGF

Identifiers

TGFA, TFGA, transforming growth factor alpha, Transforming growth factor - α

External IDs

OMIM: 190170 MGI: 98724 HomoloGene: 2431 GeneCards: TGFA

Gene ontology
Molecular function	• epidermal growth factor receptor binding • protein binding • growth factor activity
Cellular component	• integral component of membrane • endoplasmic reticulum membrane • membrane • plasma membrane • integral component of plasma membrane • extracellular region • cell surface • basolateral plasma membrane • perinuclear region of cytoplasm • ER to Golgi transport vesicle membrane • endoplasmic reticulum-Golgi intermediate compartment membrane • cytoplasmic vesicle • Golgi membrane • extracellular space
Biological process	• positive regulation of epidermal growth factor-activated receptor activity • positive regulation of epithelial cell proliferation • ER to Golgi vesicle-mediated transport • COPII vesicle coating • activation of MAPK activity • cell proliferation • positive regulation of mitotic nuclear division • positive regulation of cell division • regulation of transcription from RNA polymerase II promoter
Sources:Amigo / QuickGO

RNA expression pattern

PBB GE TGFA 205016 at fs.png

PBB GE TGFA 205015 s at fs.png

PBB GE TGFA 211258 s at fs.png

More reference expression data

Orthologs

Species

Human

Mouse


7039


21802


ENSG00000163235


ENSMUSG00000029999


P01135


P48030

RefSeq (mRNA)


NM_001099691 NM_001308158 NM_001308159 NM_003236


NM_031199

RefSeq (protein)


NP_001093161 NP_001295087 NP_001295088 NP_003227


NP_112476.1 NP_112476

Location (UCSC)

Chr 2: 70.45 – 70.55 Mb

Chr 6: 86.2 – 86.28 Mb

PubMed search

1GK5, 1MOX, 1YUF, 1YUG, 2TGF, 3E50, 3TGF, 4TGF

ENSG00000163235

ENSMUSG00000029999

NM_001099691
NM_001308158
NM_001308159
NM_003236

NP_001093161
NP_001295087
NP_001295088
NP_003227

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Wikipedia

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