TCF4

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
2KWF

Identifiers

TCF4, E2-2, ITF-2, ITF2, PTHS, SEF-2, SEF2, SEF2-1, SEF2-1A, SEF2-1B, SEF2-1D, TCF-4, bHLHb19, FECD3, transcription factor 4

External IDs

Gene ontology
Molecular function	• protein dimerization activity • protein homodimerization activity • transcription factor activity, sequence-specific DNA binding • transcription factor activity, TFIIB-class binding • transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting • transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding • bHLH transcription factor binding • E-box binding • protein C-terminus binding • protein binding • identical protein binding • TFIIB-class transcription factor binding • protein heterodimerization activity • DNA binding • RNA polymerase II core promoter proximal region sequence-specific DNA binding
Cellular component	• transcription factor complex • nuclear chromatin • nucleus • protein-DNA complex
Biological process	• cell differentiation • regulation of transcription, DNA-templated • protein-DNA complex assembly • transcription, DNA-templated • nervous system development • positive regulation of transcription, DNA-templated • DNA-templated transcription, initiation • transcription initiation from RNA polymerase II promoter • positive regulation of transcription from RNA polymerase II promoter • positive regulation of neuron differentiation
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse

Entrez


6925


21413


ENSG00000196628


ENSMUSG00000053477


P15884


Q60722

RefSeq (mRNA)

NM_001083962 NM_001243226 NM_001243227 NM_001243228 NM_001243230
NM_001243231 NM_001243232 NM_001243233 NM_001243234 NM_001243235 NM_001243236 NM_001306207 NM_001306208 NM_003199 NM_001330604 NM_001330605 NM_001348211 NM_001348212 NM_001348213 NM_001348214 NM_001348215 NM_001348216 NM_001348217 NM_001348218 NM_001348219 NM_001348220


NM_001083967 NM_013685

RefSeq (protein)

NP_001077431 NP_001230155 NP_001230156 NP_001230157 NP_001230159
NP_001230160 NP_001230161 NP_001230162 NP_001230163 NP_001230164 NP_001230165 NP_001293136 NP_001293137 NP_001317533 NP_001317534 NP_003190 NP_001335140 NP_001335141 NP_001335142 NP_001335143 NP_001335144 NP_001335145 NP_001335146 NP_001335147 NP_001335148 NP_001335149


NP_001077436 NP_038713

Location (UCSC)

PubMed search