Switzerland participated in the Eurovision Song Contest 2012 in Baku, Azerbaijan. The Swiss entry was selected through Die grosse Entscheidungs Show, a national final organised by the Swiss broadcaster SRG SSR. Sinplus represented Switzerland with the song "Unbreakable", which failed to qualify from the first semi-final, achieving 11th place with 45 points.

On 22 July 2011, SF announced that 14 entries would join the national final from the Bodensee Arena in Kreuzlingen, two more than the previous year.

Six songs would come from an internet voting of German-language SF, three from radio broadcaster DRS 3, three from French-language broadcaster RTS, and two from Italian-language RSI. In an unusual twist, the participants would sing two-minute abridged versions of their songs at the final, despite the competition rules set out by SF that submitted songs had to be between 2:55-3:00 minutes in length.

The overall SF selection selected six finalists. Candidates could submit entries to the broadcaster from 1–30 September 2011. 221 songs were sent to SF. The first Eurovision winner Lys Assia, the Danish Eurovision entry in 2007 DQ (as Peter Andersen), German Idol participant Zazou Mall and US-pop singer Ultra Naté send their entries to SF, as well as the first South African Idols winner Heinz Winckler and former The X Factor (UK) participants Same Difference and Maria Lawson. A 50/50 mix of internet voting and the verdict of an expert jury decided on the finalists. On November 10, the Swiss HoD announced via Twitter that Lys Assia was one of the 6 qualified acts. The complete line-up was announced officially on the following day.

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