Sulfite oxidase

sulfite oxidase
Sulfite oxidase catalyses the oxidation-reduction reaction of sulfite and water, yielding sulfate.
Identifiers
EC number	1.8.3.1
CAS number	9029-38-3
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / EGO
Search PMC articles PubMed articles NCBI proteins

SUOX
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1MJ4
Identifiers
Aliases	SUOX, entrez:6821
External IDs	OMIM: 606887 MGI: 2446117 HomoloGene: 394 GeneCards: SUOX
Gene ontology Molecular function • molybdopterin cofactor binding • molybdenum ion binding • oxidoreductase activity • sulfite oxidase activity • heme binding • metal ion binding • protein binding Cellular component • mitochondrial matrix • mitochondrial intermembrane space • mitochondrion Biological process • sulfur compound metabolic process • sulfide oxidation, using sulfide:quinone oxidoreductase • oxidation-reduction process • nitrate assimilation Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	6821	211389
Ensembl	ENSG00000139531	ENSMUSG00000049858
UniProt	P51687	Q8R086
RefSeq (mRNA)	NM_000456 NM_001032386 NM_001032387	NM_173733
RefSeq (protein)	NP_000447 NP_001027558 NP_001027559	NP_776094.2 NP_776094
Location (UCSC)	Chr 12: 56 – 56.01 Mb	Chr 10: 128.67 – 128.67 Mb
PubMed search

1MJ4

6821

211389

ENSG00000139531

ENSMUSG00000049858

P51687

Q8R086

NM_000456
NM_001032386
NM_001032387

NM_173733

NP_000447
NP_001027558
NP_001027559

NP_776094.2
NP_776094

Sulfite oxidase (EC 1.8.3.1) is an enzyme in the of all eukaryotes. It oxidizes sulfite to sulfate and, via , transfers the electrons produced to the electron transport chain, allowing generation of ATP in oxidative phosphorylation. This is the last step in the metabolism of sulfur-containing compounds and the sulfate is excreted.