St. Anna is an unincorporated community in Calumet and Sheboygan Counties in the U.S. state of Wisconsin. It lies in the towns of Russell and New Holstein.
St. Anna priest Rev. John Haen described the St. Anna area prior to European emigrants "The land at the coming of the early settlers in this vicinity was covered with dense forests which had not been touched by woodmen's axe. The soil was rich and fertile for no plowshare had entered. The woods were teeming with deer and other wild animals hunted only by the Brothertown Indians who inhabited this region." In 1848, 70 emigrants from Hamburg, Germany settled in the New Holstein area, forming the basis of what would become the present city of New Holstein. St. Anna's development began in the fall of 1848 when some of these German Roman Catholics built a log church. The church had added a school by 1878. By 1881, St. Anna consisted of a wooden shoe factory, several general stores, and two hotels. The Chilton Times-Journal said that St. Anna was "once the center of the wooden shoe industry in Wisconsin." The cornerstone for community's new brick block church was laid on November 4, 1895 and the structure is still used (as of 2014). St. Anna had a post office as of 1876.
St. Anna is located at the edge of an area in eastern Fond du Lac County, Wisconsin known as "The Holyland", so called because of the large number of communities built around churches, including St. Peter, St. Cloud, Marytown, Mount Calvary, Johnsburg, Calvary, Brothertown and Jericho.