Src kinase

CSK

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
1BYG, 1CSK, 3D7T, 3D7U, 3EAC, 3EAZ

Identifiers

Aliases

CSK, Src, c-src tyrosine kinase, CSK/Src, non-receptor tyrosine kinase

External IDs

MGI: 88537 HomoloGene: 55818 GeneCards: CSK

Gene ontology
Molecular function	• transferase activity • nucleotide binding • protein kinase activity • protein kinase A catalytic subunit binding • non-membrane spanning protein tyrosine kinase activity • metal ion binding • protein C-terminus binding • protein binding • identical protein binding • protein tyrosine kinase activity • protein phosphatase binding • proline-rich region binding • receptor binding • ATP binding • kinase activity
Cellular component	• cytoplasm • cytosol • membrane • cell-cell junction • extrinsic component of cytoplasmic side of plasma membrane • plasma membrane • membrane raft • extracellular exosome
Biological process	• cell differentiation • adaptive immune response • positive regulation of MAP kinase activity • epidermal growth factor receptor signaling pathway • negative regulation of phagocytosis • phosphorylation • transmembrane receptor protein tyrosine kinase signaling pathway • negative regulation of low-density lipoprotein particle clearance • immune system process • negative regulation of interleukin-6 production • T cell costimulation • oligodendrocyte differentiation • negative regulation of Golgi to plasma membrane protein transport • regulation of Fc receptor mediated stimulatory signaling pathway • regulation of cytokine production • protein phosphorylation • brain development • cellular response to peptide hormone stimulus • regulation of cell proliferation • peptidyl-tyrosine autophosphorylation • negative regulation of ERK1 and ERK2 cascade • protein autophosphorylation • innate immune response • adherens junction organization • T cell receptor signaling pathway • negative regulation of cell proliferation • negative regulation of bone resorption • negative regulation of kinase activity • central nervous system development
Sources:Amigo / QuickGO

RNA expression pattern

More reference expression data

Orthologs

Species

Human

Mouse

Entrez


1445


12988

Ensembl


ENSG00000103653


ENSMUSG00000032312

UniProt


P41240


P41241

RefSeq (mRNA)


NM_001127190 NM_004383


NM_007783 NM_001304761

RefSeq (protein)


NP_001120662 NP_004374


NP_001291690.1 NP_031809.2 NP_001291690 NP_031809

Location (UCSC)

Chr 15: 74.78 – 74.8 Mb

Chr 9: 57.63 – 57.65 Mb

PubMed search

1BYG, 1CSK, 3D7T, 3D7U, 3EAC, 3EAZ

NM_001127190
NM_004383

NM_007783
NM_001304761

NP_001120662
NP_004374

NP_001291690.1
NP_031809.2
NP_001291690
NP_031809

...
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