Speke (/ˈspiːk/) is an area of Liverpool, Merseyside, England, close to the boundaries of the Metropolitan Borough of Knowsley. It is 7.7 miles (12.4 km) south east of the city centre and to the west of the town of Widnes.
Speke is bordered by a number of other areas; Garston, Hunts Cross, Halewood and Hale Village and is located near to the widest part of the River Mersey.
The name derives from the Old English Spec, meaning 'brushwood'. It was known as Spec in the Domesday Book, which gave Speke Hall as one of the properties held by Uctred. (Today Speke Hall, now a Tudor wood-framed house, is open to the public.)
In the mid 14th century, the manors of Speke, Whiston, Skelmersdale, and Parr were held by William Dacre, 2nd Baron Dacre.
Until the 1930s, Speke was a small village with a population of 400; by the end of the 1950s more than 25,000 people were living in the area. The local All Saints Church was built by the last resident owner of Speke Hall, Miss Adelaide Watt.