Princess Sophia of Prussia (Sophia Dorothea Ulrike Alice; 14 June 1870 – 13 January 1932), was Queen Consort of the Hellenes during 1913–1917 and 1920–1922.

A member of the House of Hohenzollern and daughter of Emperor Frederick III of Germany, Sophia received a liberal and anglophile education, under the supervision of her mother, Victoria, Princess Royal. In 1889, less than a year after the death of her father, she married her third cousin the Diadochos Constantine, Duke of Sparta and heir of the Greek throne. After a difficult period of adaptation in her new country, Sophia gave birth to six children and became involved in the assistance to the poor, following in the footsteps of her mother-in-law, Queen Olga. However, it was during the wars which Greece faced during the end of the 19th and the beginning of the 20th century that Sophia showed the most social activity: she founded field hospitals, oversaw the training of Greek nurses and even she herself healed wounded soldiers.

However, Sophia was hardly rewarded for her actions, even after her grandmother, Queen Victoria, decorated her with the Royal Red Cross after the Thirty Days' War: the Greeks criticized her links with Germany. Her brother, Emperor William II was indeed an ally of the Ottoman Empire and openly opposed the construction of the Megali Idea, which could established a Greek state that would encompass all ethnic Greek-inhabited areas. During World War I, the blood ties between Sophia and the German Emperor also cause the suspicion of the Triple Entente, which accuses Constantine I for his neutrality in the conflict.

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