Somatostatin receptor 1

SSTR1
Identifiers
Aliases	SSTR1, SRIF-2, SS-1-R, SS1-R, SS1R, Somatostatin receptor 1
External IDs	MGI: 98327 HomoloGene: 820 GeneCards: SSTR1
Gene ontology Molecular function • G-protein coupled receptor activity • neuropeptide binding • signal transducer activity • somatostatin receptor activity Cellular component • cytoplasm • integral component of membrane • membrane • plasma membrane • integral component of plasma membrane • neuron projection Biological process • G-protein coupled receptor signaling pathway • glutamate receptor signaling pathway • response to nutrient • somatostatin signaling pathway • cell-cell signaling • G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger • digestion • cellular response to estradiol stimulus • cerebellum development • cell surface receptor signaling pathway • spermatogenesis • response to starvation • forebrain development • neuropeptide signaling pathway • signal transduction • negative regulation of cell proliferation Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	6751	20605
Ensembl	ENSG00000139874	ENSMUSG00000035431
UniProt	P30872	P30873
RefSeq (mRNA)	NM_001049	NM_009216
RefSeq (protein)	NP_001040	NP_033242.1 NP_033242
Location (UCSC)	Chr 14: 38.21 – 38.21 Mb	Chr 12: 58.21 – 58.21 Mb
PubMed search

6751

20605

ENSG00000139874

ENSMUSG00000035431

P30872

P30873

NM_001049

NM_009216

NP_001040

NP_033242.1
NP_033242

Somatostatin receptor type 1 is a protein that in humans is encoded by the SSTR1 gene.

Somatostatin acts at many sites to inhibit the release of many hormones and other secretory proteins. The biological effects of somatostatin are probably mediated by a family of G protein-coupled receptors that are expressed in a tissue-specific manner. The encoded protein is a member of the superfamily of somatostatin receptors having seven transmembrane segments, and is expressed in highest levels in jejunum and stomach.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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