"Skinny Little Bitch" is a song by the American alternative rock band Hole. It is the second track and lead single from the band's fourth studio album, Nobody's Daughter, and was released on March 12, 2010 on Mercury Records. Written by vocalist Courtney Love and lead guitarist Micko Larkin, "Skinny Little Bitch" was Hole's first single in a decade and first release not to feature founding member Eric Erlandson.

The song premiered on the New York radio station WRXP on March 3, 2010 and was released to American radio on March 9. During the first week of its radio release, the song became the most added on alternative radio and the second most added on active rock in the United States. A digital download of the single was officially made available on March 12 and a limited edition colored 10" was released as part of Record Store Day 2010 on April 17.

Two official music videos for "Skinny Little Bitch" have been released on Hole's official YouTube channel—a multi-camera version of the band's performance at SXSW in March 2010 and a shortened video of Love performing the song while getting a tattoo. Other plans for a music video, including an animation by Michael Mouris and a video featuring model Sasha Pivovarova, were considered but never received a greenlight from Mercury Records.

"Skinny Little Bitch" was added to the US Active Rock Charts at #32 making it the first song with lead vocals from a female to ever make the chart.

The track was described by NME as,

"a balls-out, low-down dirty rock song, and as fine a signature tune for the new Hole as you could imagine. Tapping the same lyrical vein as 'Samantha', it's The Stooges fronted by a Joan Jett re-imagined as the Bride Of Frankenstein. And it’s the sound of Courtney having fun."

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