Skil

SKIL

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
3EQ5

Identifiers

SKIL, SNO, SnoA, SnoI, SnoN, SKI-like proto-oncogene

External IDs

MGI: 106203 HomoloGene: 3948 GeneCards: SKIL

Gene ontology
Molecular function	• DNA binding • transcription corepressor activity • protein domain specific binding • protein complex binding • RNA polymerase II core promoter proximal region sequence-specific DNA binding • transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding • protein binding • chromatin binding • SMAD binding
Cellular component	• cytoplasm • PML body • nucleoplasm • protein complex • acrosomal vesicle • nucleus
Biological process	• positive regulation of extrinsic apoptotic signaling pathway via death domain receptors • response to cytokine • lymphocyte homeostasis • response to antibiotic • negative regulation of transcription from RNA polymerase II promoter • blastocyst formation • positive regulation of axonogenesis • protein homotrimerization • lens fiber cell differentiation • positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage • cell cycle arrest • spermatogenesis • protein heterotrimerization • response to growth factor • skeletal muscle tissue development • negative regulation of BMP signaling pathway • regulation of apoptotic process • negative regulation of cell differentiation • transforming growth factor beta receptor signaling pathway • negative regulation of transforming growth factor beta receptor signaling pathway • neuron development
Sources:Amigo / QuickGO

RNA expression pattern

PBB GE SKIL 206675 s at tn.png

More reference expression data

Orthologs

Species

Human

Mouse


6498


20482


ENSG00000136603


ENSMUSG00000027660


P12757


Q60665

RefSeq (mRNA)


NM_001145097 NM_001145098 NM_001248008 NM_005414


NM_001039090 NM_001271772 NM_011386

RefSeq (protein)


NP_001138569 NP_001138570 NP_001234937 NP_005405


NP_001034179.1 NP_035516.2 NP_001034179 NP_001258701 NP_035516

Location (UCSC)

Chr 3: 170.36 – 170.4 Mb

Chr 3: 31.1 – 31.12 Mb

PubMed search

ENSG00000136603

ENSMUSG00000027660

NM_001145097
NM_001145098
NM_001248008
NM_005414

NM_001039090
NM_001271772
NM_011386

NP_001138569
NP_001138570
NP_001234937
NP_005405

NP_001034179.1
NP_035516.2
NP_001034179
NP_001258701
NP_035516

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Wikipedia

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