The Sixty Years' War (1754–1814) was a military struggle for control of the Great Lakes region in North America, encompassing a number of wars over several generations. The term Sixty Years' War is not widely known, and is used primarily by academic historians who specialize in various aspects of the conflict. Traditionally, the war for control of the Great Lakes region has been written about only in reference to the individual wars; the designation Sixty Years' War provides a framework for viewing this era as a continuous whole.
As defined by historian David Skaggs, the Sixty Years' War consists of six phases:
1. French and Indian War (1754–1763)
2. Pontiac's Rebellion (1763–1765)
3. Lord Dunmore's War (1774)
4. Frontier warfare during the American Revolution (1775–1783)
5. Northwest Indian War (1785–1795)
6. War of 1812 (1812–1814)