"Sittin' Up in My Room" is a song by American recording artist Brandy Norwood. It was written and produced by Babyface and recorded by Norwood for the soundtrack of the 1995 film Waiting to Exhale, starring Whitney Houston and Angela Bassett. The track was one out of five singles the album spawned and reached number two on the US Billboard Hot 100, becoming Norwood's most successful single on that particular chart up to that point. It is of note that the characteristic bass intro is a replica of the famous riff performed by bassist Larry Graham, of Sly and the Family Stone, on their hit "Thank You (Falettinme Be Mice Elf Agin)".

"Sittin' Up in My Room" was performed on several television and award show ceremonies, such as Late Show with David Letterman, the 23rd Annual American Music Awards, the 1996 Soul Train Awards, the 39th Annual Grammy Awards, and the 2015 Soul Train Music Awards. A music video was also filmed, depicting Brandy keeping herself penned up in a retro, brightly-colored room after her friend tells her that her love interest is joining the party downstairs. Actor Donald Faison appears as her love interest in the video, directed by Hype Williams. It was nominated for Best Song from a Movie and Best Video from a Film at the 1996 MTV Awards. The song has since been performed on several awards shows and Norwood's concerts and tours, including the 1998 Never Say Never World Tour and the 2016 Slayana World Tour.