Sir Charles Sherrington

Sir Charles Scott Sherrington OM GBE PRS FRCP FRCS

Born	(1857-11-27)27 November 1857 Islington, Middlesex, England, United Kingdom
Died	4 March 1952(1952-03-04) (aged 94) Eastbourne, Sussex, England, United Kingdom
Citizenship	British
Fields	Physiology Pathology Histology Neurology Bacteriology
Alma mater	Ipswich School Royal College of Surgeons of England University of Cambridge
Academic advisors	Michael Foster John Newport Langley
Doctoral students	John Farquhar Fulton John Carew Eccles Alfred Fröhlich
Influences	Johannes Müller Thomas Ashe Jean Fernel Thomas Browne Rudolf Virchow
Influenced	Sir John Eccles Ragnar Granit Howard Florey E.M. Tansey Archibald Hill Wilder Penfield
Notable awards	FRS (1893) Royal Medal (1905) Copley Medal (1927) Nobel Prize in Physiology or Medicine (1932)

Sir Charles Scott Sherrington OM GBE PRS FRCP FRCS (27 November 1857 – 4 March 1952) was an English neurophysiologist, histologist, bacteriologist, and a pathologist, Nobel laureate and president of the Royal Society in the early 1920s. He received the Nobel Prize in Physiology or Medicine with Edgar Adrian, 1st Baron Adrian, in 1932 for their work on the functions of neurons. Prior to the work of Sherrington and Adrian, it was widely accepted that reflexes occurred as isolated activity within a reflex arc. Sherrington received the prize for showing that reflexes require integrated activation and demonstrated reciprocal innervation of muscles (Sherrington's law). Through his seminal 1906 publication, The Integrative Action of the Nervous System, he had effectively laid to rest the theory that the nervous system, including the brain, can be understood as a single interlinking network. His alternative explanation of synaptic communication between neurons helped shape our understanding of the central nervous system.