The Sack of Brescia took place on February 18, 1512 during the War of the League of Cambrai. The city of Brescia had revolted against French control, garrisoning itself with Venetian troops. Gaston de Foix, recently arrived to command the French armies in Italy, ordered the city to surrender; when it refused, he attacked it with around 12,000 men. The French attack took place in a pouring rain, through a field of mud; Foix ordered his men to remove their shoes for better traction. The defenders inflicted heavy casualties on the French, but were eventually overrun, suffering 8,000 – 15,000 casualties. The Gascon infantry and landsknechts then proceeded to thoroughly sack the city, massacring thousands of civilians over the next five days. Following this, the city of Bergamo paid some 60,000 ducats to the French to avoid a similar fate.
The kingdoms of France and Scotland had traditionally enjoyed a close diplomatic relationship, reflected in a defensive treaty signed between the two kingdoms in 1512. When Henry crossed the English Channel to campaign in France, the King of France activated the treaty, sending arms, money and military advisers to James IV of Scotland to encourage him to fulfil his obligations, in the hope that this would draw English resources away from the invasion of France. James crossed the border with a force of some 35,000 men, including 5,000 French advisers. He was opposed by an English force under the Earl of Surrey. The two sides met on September 9, 1513, near the village of Flodden. The Scottish army was heavily defeated, losing some 9,000 men and many nobles, including King James, the King's illegitimate son, and twelve earls.