Seneca High School is a high school located in Seneca, Missouri at 1110 Neosho Street.
Its enrollment in 2016-17 was approximately 420, and its student-to-teacher ratio is a high 14:1. The school is part of the Seneca R-VII school system, in Newton County, Missouri.
The school colors are Red (primary), White (secondary), and Blue (tertiary), their mascot is the Indian, and they play in the Big 8 Conference.
The district is bounded by the Joplin, Missouri school district to the north, the Neosho, Missouri district to the east, the McDonald County district to the south, and the Missouri state border to the west.
Coordinates: 36°50′16″N 94°36′23″W / 36.83790°N 94.60628°W