Seminole Heights is a historic neighborhood and district located in central Tampa. It includes many early 20th century bungalow homes and historic buildings. It was an early residential area of Tampa connected by streetcar. The area had an economic downturn in the late 20th century marked by increased crime, but has since seen a resurgence with new restaurants, brew pubs and independent businesses opening up. The neighborhood's historic homes, eclectic shops and gourmet restaurants are an increasing draw.

As of the 2000 census, the district had a population of 24,567.

Seminole Heights is known for its historic craftsman style bungalows from the early 20th century. Many buildings in the neighborhood existed in the early 1900s, including the Seminole Heights Methodist Church, Seminole Heights Elementary School, Broward Elementary, Hillsborough High School, and St. Paul's Lutheran Church. The Seminole Heights Garden Center, a neighborhood park, is used for community events such as art festivals and picnics. Seminole Heights has the longest stretch of Riverfront parkland in the city of Tampa. Rivercrest, Epps, and several pocket parks provide access to the Hillsborough River.

In recent years Seminole Heights has experienced rising property values and a decrease in crime. The area is popular among young professionals and their families who are seeking an alternative to master planned communities. The area contains two designated historical districts including Seminole Heights (local and national designation), Hampton Terrace (national designation).

In 2003, Southeast Seminole Heights was named Best Neighborhood in America by NUSA.

In July 2009, This Old House Magazine ranked Seminole Heights among the best places to buy an old house for: families, green thumbs, cottages and bungalows, single women homebuyers, porch sitters, walkers, and the south. Overall, Seminole Heights was in the top eight of editors picks.

Also in recent years, the district has become known as a dining destination. Notable restaurant/ bars include the two-time James Beard Award nominee The Refinery, the Independent Bar & Cafe', and Ella's Americana Folk Art Cafe.

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