Selenophosphate synthetase 1

SEPHS1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 3FD5, 3FD6
Identifiers
Aliases	SEPHS1, SELD, SPS, SPS1, Selenophosphate synthetase 1
External IDs	MGI: 1923580 HomoloGene: 56558 GeneCards: SEPHS1
Gene location (Human) Chr. Chromosome 10 (human) Band No data available Start 13,317,424 bp End 13,348,298 bp
Gene location (Mouse) Chr. Chromosome 2 (mouse) Band No data available Start 4,881,564 bp End 4,910,557 bp
RNA expression pattern More reference expression data
Gene ontology Molecular function • transferase activity • nucleotide binding • selenide, water dikinase activity • GTP binding • protein binding • ATP binding • protein homodimerization activity • identical protein binding • protein heterodimerization activity • kinase activity Cellular component • cytoplasm • plasma membrane • nuclear membrane • membrane • nucleus Biological process • cellular protein modification process • phosphorylation • selenocysteine biosynthetic process Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	22929	109079
Ensembl	ENSG00000086475	ENSMUSG00000026662
UniProt	P49903 Q5T5U7	Q8BH69
RefSeq (mRNA)	NM_001195602 NM_001195604 NM_012247	NM_175400
RefSeq (protein)	NP_001182531 NP_001182533 NP_036379	NP_780609
Location (UCSC)	Chr 10: 13.32 – 13.35 Mb	Chr 10: 4.88 – 4.91 Mb
PubMed search

3FD5, 3FD6

22929

109079

ENSG00000086475

ENSMUSG00000026662

P49903
Q5T5U7

Q8BH69

NM_001195602
NM_001195604
NM_012247

NM_175400

NP_001182531
NP_001182533
NP_036379

NP_780609

Selenide, water dikinase 1 is an enzyme that in humans is encoded by the SEPHS1 gene.

This protein encodes an enzyme that synthesizes selenophosphate from selenide and ATP. Selenophosphate is the selenium donor used to synthesize selenocysteine, which is co-translationally incorporated into selenoproteins at in-frame UGA codons.

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Wikipedia