See of Larissa

The Metropolis of Larissa and Tyrnavos (Greek: Ιερά Μητρόπολις Λαρίσης και Τυρνάβου) is a Greek Orthodox metropolitan see in Thessaly, Greece. The current metropolitan is, since 1994, Ignatios Lappas ().

Christianity penetrated early to Larissa, though its first bishop is recorded only in 325 at the Council of Nicaea.Saint Achillius of Larissa, of the 4th century, is celebrated for numerous miracles.

Michel Le Quien cites twenty-nine bishops from the fourth to the 18th centuries.

In the Ecumenical Council of Ephesus in 431, the Bishop of Larissa is already mentioned as metropolitan bishop of Thessaly, and some of his suffragans who participated in the council were the bishops of Pharsalus, Lamia, Thessalian Thebes, Echinos, Hypate (Ypati), Kaisareia, and Demetrias. Some time between 730 and 751, the Church in Thessaly, along with the rest of the Illyricum, were transferred from the jurisdiction of the Pope in Rome to that of the Patriarch of Constantinople. Bishop Vigilantius attended the Council of Chalcedon.