San Gaetano, also known as Santi Michele e Gaetano, is a Baroque church in Florence, Italy, located on the Piazza Antinori.
A Romanesque church, dedicated solely to Saint Michael the Archangel, had been located at the site for centuries prior to its Baroque reconstruction. Patronized by the Theatine order, the new church was dedicated to Saint Cajetan, one of the founders of the order, though the church could not formally be named after him until his canonisation in 1671. Funding for this reconstruction was obtained from the noble families in Florence, including the Medicis. Cardinal Carlo de' Medici was particularly concerned with the work, and his name is inscribed on the façade. Building took place between 1604 and 1648. The original designs were by Bernardo Buontalenti but a number of architects had a hand in building it, each of whom changed the design. The most important architects were Matteo Nigetti and Gherardo Silvani.
In 2008, the church was entrusted to the Institute of Christ the King Sovereign Priest, a traditional institute of clerical life.
The façade, with its sculptural decorations, is atypical for Florentine churches, which had a predilection for geometrically ornamented façades. It has three portals: the center portal has a triangular tympanum surmounted by reclining marble statues representing Faith and Charity, sculpted by the Flemish Baldassarre Delmosel. In the center above the door is the heraldic shield of the Theatine order; higher above is the shield of Cardinal Giovanni Carlo de Medici, a prominent patron. Above the side doors are a statue of St Cajetan (right, by the same Delmosel) and St Andrew Avellino (left, by Francesco Andreozzi).