Sancia di Castiglia is an Italian opera seria in two acts by Gaetano Donizetti to a libretto by Pietro Salatino. It was first performed at the Teatro San Carlo in Naples, on 4 November 1832 conducted by Nicola Festa.
Sancia, Queen of Castile, whose husband has been killed in battle, also believes that her son, Garcia, has been killed. She plans to marry the Saracen prince, Ircano, against the advice of her minister, Rodrigo. When Garcia, having survived an assassination attempt instigated by Ircano, reappears to claim the throne, Ircano tells Sancia that he will marry her only if she poisons her son. Garcia is about to drink from the poisoned goblet when a suddenly repentant Sancia snatches it and drinks it herself. She dies pleading for her son's forgiveness.
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