Samuel Nott (11 September 1788 – 1 June 1869) was one of the pioneers of American foreign missions. He was one of the first five foreign missionaries under American Board of Commissioners for Foreign Missions to India, and established Bombay Mission station, the first Americans overseas mission station at Bombay, then-headquarters of Bombay Presidency.
He published several sermons and books, notably, Sixteen Years' Preaching and Procedure at Wareham, Slavery and the Remedy, and many more.
Nott was born on 11 September 1788 in Franklin, Connecticut. His father Samuel Nott Sr. (1754–1852) was the pastor of Congregational Church, Franklin; and patriarch of the New England clergy. Nott Jr. was admitted to his father's church in 1805. Under the guidance of his father, his education commenced in his early childhood.
He graduated at Union College in July 1808, and at Andover Theological Seminary in 1808. While studying at Andover, a group of like-minded Christians, namely, Adoniram Judson, Samuel Newell, Luther Rice, Gordon Hall, and Samuel John Mills presented their enthusiasm for overseas missionary service to General Association of Congregational Churches, Bradford, Massachusetts; later, in 1812 Mills led the establishment of American Board of Commissioners for Foreign Missions (ABCFM), the first foreign mission agency in North America. He, including Newell, Judson, Hall, Rice, and Mills were ordained by the ABCFM on 6 February 1812; accordingly, Judson, Newell, Nott and their wives, Hall, and Rice were sent as first five American missionaries to India in 1812. However, Mills stayed back in United States to oversee their cause.