Saint Jo Independent School District is a public school district based in Saint Jo, Texas (USA).
Located in Montague County, a small portion of the district extends into Cooke County.
In 2009, the school district was rated "recognized" by the Texas Education Agency.
Saint Jo has fielded a football team every season since 1924. Their first game in school history was a 25-0 loss to the Nocona Indians. St. Jo continued to play one or two games a year until the mid 1930s. It was during this time St. Jo captured the first win in Panther history, a 7-6 upset of Bowie. They followed up this victory with two routs of local Bellevue by a combined score of 119-0. The Panthers continued to improve through the years, notching winning seasons in 1941 and 1948. In the early 1950s, St. Jo developed a rivalry with the local Muenster Hornets. The game's winner annually was awarded the Coveted Horseshoe. St. Jo won their first shoe after a 20-12 victory over the Big Red in 1952. The mid-1960s were the glory years for Panther football. From 1963-66 the maroon and white compiled a 35-8 record, two bi-district championships, and an impressive 4-year winning streak over Muenster.