The Societé Anonyme Belge d'Exploitation de la Navigation Aérienne, (French; "Belgian Corporation for Air Navigation Services"), better known internationally by the acronym Sabena or SABENA, was the national airline of Belgium from 1923 to 2001, with its base at Brussels National Airport. After its bankruptcy in 2001, the newly formed SN Brussels Airlines took over part of Sabena's assets in February 2002, which became Brussels Airlines after a merger with Virgin Express in March 2007. The airline's corporate headquarters were located in the Sabena House on the grounds of Brussels Airport in Zaventem.

Sabena began operations on 23 May 1923 as the national carrier of Belgium. The airline was created by the Belgian government after their predecessor SNETA (Syndicat national pour l'étude des transports aériens) - formed in 1919 to pioneer commercial aviation in Belgium - ceased operations. Sabena operated its first commercial flight from Brussels to London (UK) on 1 July 1923, via Ostend. Services to Rotterdam (Netherlands) and Strasbourg (France) were launched on 1 April 1924. The Strasbourg service was extended to Basle (Switzerland) on 10 June 1924. Amsterdam (Netherlands) was added on 1 September 1924, and Hamburg (Germany) followed on 1 May 1929 via Antwerp, Düsseldorf, and Essen.

When Sabena was created, the airline was partly funded by Belgians in the Belgian Congo colony who lost their air service, an experimental passenger and cargo company (LARA) between Léopoldville, Lisala, and Stanleyville a year earlier and who expected the new Belgian national airline to fill this gap. On 12 February 1925, Sabena pioneered a long haul across Africa to Leopoldville, capital of the Belgian Congo. Throughout their history, Sabena had a long tradition of service to African destinations and for a long time these were the only profitable routes served by the airline.

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