SUZ12

SUZ12
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 5IJ7, 5IJ8, 5HYN
Identifiers
Aliases	SUZ12, CHET9, JJAZ1, SUZ12 polycomb repressive complex 2 subunit
External IDs	MGI: 1261758 HomoloGene: 32256 GeneCards: SUZ12
Gene ontology Molecular function • histone methyltransferase activity • sequence-specific DNA binding • chromatin binding • metal ion binding • methylated histone binding • protein binding • RNA binding • RNA polymerase II core promoter sequence-specific DNA binding • chromatin DNA binding • promoter-specific chromatin binding Cellular component • sex chromatin • ESC/E(Z) complex • nucleoplasm • protein-DNA complex • nucleolus • nucleus • RSC complex • nuclear body Biological process • negative regulation of cell differentiation • negative regulation of transcription from RNA polymerase II promoter • transcription, DNA-templated • negative regulation of gene expression, epigenetic • positive regulation of cell proliferation • histone methylation • histone ubiquitination • covalent chromatin modification • regulation of transcription, DNA-templated Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	23512	52615
Ensembl	ENSG00000178691	ENSMUSG00000017548
UniProt	Q15022	Q80U70
RefSeq (mRNA)	NM_015355 NM_001321207	NM_001163018 NM_199196
RefSeq (protein)	NP_001308136 NP_056170	NP_001156490.1 NP_954666.1 NP_001156490 NP_954666
Location (UCSC)	Chr 17: 31.94 – 32 Mb	Chr 11: 79.99 – 80.03 Mb
PubMed search

5IJ7, 5IJ8, 5HYN

23512

52615

ENSG00000178691

ENSMUSG00000017548

Q15022

Q80U70

NM_015355
NM_001321207

NM_001163018
NM_199196

NP_001308136
NP_056170

NP_001156490.1
NP_954666.1
NP_001156490
NP_954666

Polycomb protein SUZ12 is a protein that in humans is encoded by the SUZ12 gene.

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