SULT2A1

SULT2A1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1EFH, 1J99, 1OV4, 2QP3, 2QP4, 3F3Y, 4IFB
Identifiers
Aliases	SULT2A1, DHEA-ST, DHEAS, HST, ST2, ST2A1, ST2A3, STD, hSTa, sulfotransferase family 2A member 1
External IDs	MGI: 98430 HomoloGene: 37741 GeneCards: SULT2A1
Gene ontology Molecular function • transferase activity • sulfotransferase activity • protein binding • bile-salt sulfotransferase activity • estrone sulfotransferase activity • steroid sulfotransferase activity • aryl sulfotransferase activity Cellular component • cytoplasm • cytosol Biological process • lipid catabolic process • digestion • bile acid catabolic process • steroid metabolic process • 3'-phosphoadenosine 5'-phosphosulfate metabolic process • sulfation • lipid metabolic process Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	6822	20859
Ensembl	ENSG00000105398	ENSMUSG00000078798
UniProt	Q06520	P52843
RefSeq (mRNA)	NM_003167	NM_001111296
RefSeq (protein)	NP_003158	NP_001104766.1 NP_001104766
Location (UCSC)	Chr 19: 47.87 – 47.89 Mb	Chr 7: 13.8 – 13.84 Mb
PubMed search

1EFH, 1J99, 1OV4, 2QP3, 2QP4, 3F3Y, 4IFB

6822

20859

ENSG00000105398

ENSMUSG00000078798

Q06520

P52843

NM_003167

NM_001111296

NP_003158

NP_001104766.1
NP_001104766

Bile salt sulfotransferase also known as hydroxysteroid sulfotransferase (HST) or sulfotransferase 2A1 (ST2A1) is an enzyme that in humans is encoded by the SULT2A1 gene.

Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene is primarily expressed in liver and adrenal tissues where the encoded protein sulfonates steroids and bile acids.

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