SULF1

Identifiers

SULF1, HSULF-1, SULF-1, sulfatase 1

External IDs

Gene ontology
Molecular function	• N-acetylglucosamine-6-sulfatase activity • sulfuric ester hydrolase activity • calcium ion binding • catalytic activity • hydrolase activity • metal ion binding • arylsulfatase activity
Cellular component	• endoplasmic reticulum • membrane raft • cell surface • plasma membrane • Golgi apparatus • Golgi stack • extracellular space
Biological process	• negative regulation of angiogenesis • heparan sulfate proteoglycan metabolic process • esophagus smooth muscle contraction • glomerular basement membrane development • regulation of fibroblast growth factor receptor signaling pathway • negative regulation of fibroblast growth factor receptor signaling pathway • glomerular filtration • negative regulation of endothelial cell proliferation • negative regulation of prostatic bud formation • kidney development • positive regulation of Wnt signaling pathway • vascular endothelial growth factor receptor signaling pathway • embryonic skeletal system development • bone development • positive regulation of vascular endothelial growth factor production • chondrocyte development • apoptotic process • metabolic process • positive regulation of BMP signaling pathway • negative regulation of cell migration • glial cell-derived neurotrophic factor receptor signaling pathway • cartilage development • innervation
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse

Entrez


23213


240725


ENSG00000137573


ENSMUSG00000016918


Q8IWU6


Q8K007

RefSeq (mRNA)


NM_001128204 NM_001128205 NM_001128206 NM_015170


NM_001198565 NM_001198566 NM_172294

RefSeq (protein)


NP_001121676 NP_001121677 NP_001121678 NP_055985


NP_001185494 NP_001185495 NP_758498

Location (UCSC)

PubMed search

Sulfatase 1, also known as SULF1, is an enzyme which in humans is encoded by the SULF1 gene.