STAT6

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
1OJ5, 4Y5W, 4Y5U

Identifiers

Aliases

STAT6, D12S1644, IL-4-STAT, STAT6B, STAT6C, signal transducer and activator of transcription 6

External IDs

OMIM: 601512 MGI: 103034 HomoloGene: 2373 GeneCards: STAT6

Gene ontology
Molecular function	• identical protein binding • sequence-specific DNA binding • RNA polymerase II core promoter sequence-specific DNA binding • protein phosphatase binding • DNA binding • protein binding • signal transducer activity • transcription factor activity, sequence-specific DNA binding • RNA polymerase II regulatory region sequence-specific DNA binding • transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
Cellular component	• nucleus • nucleoplasm • nuclear chromatin • membrane raft • cytoplasm • cytosol • nuclear membrane
Biological process	• regulation of transcription from RNA polymerase II promoter • T-helper 1 cell lineage commitment • regulation of cell proliferation • response to cytokine • interleukin-4-mediated signaling pathway • regulation of transcription, DNA-templated • cytokine-mediated signaling pathway • cellular response to hydrogen peroxide • mammary gland epithelial cell proliferation • cellular response to reactive nitrogen species • positive regulation of type I interferon production • positive regulation of isotype switching to IgE isotypes • mammary gland morphogenesis • negative regulation of type 2 immune response • negative regulation of transcription from RNA polymerase II promoter • signal transduction • transcription, DNA-templated • positive regulation of transcription from RNA polymerase II promoter • transcription from RNA polymerase II promoter
Sources:Amigo / QuickGO

RNA expression pattern

More reference expression data

Orthologs

Species

Human

Mouse

Entrez


6778


20852

Ensembl


ENSG00000166888


ENSMUSG00000002147

UniProt


P42226


P52633

RefSeq (mRNA)


NM_001178078 NM_001178079 NM_001178080 NM_001178081 NM_003153


NM_009284

RefSeq (protein)


NP_001171549 NP_001171550 NP_001171551 NP_001171552 NP_003144


NP_033310.2 NP_033310

Location (UCSC)

Chr 12: 57.1 – 57.13 Mb

Chr 10: 127.64 – 127.66 Mb

PubMed search

1OJ5, 4Y5W, 4Y5U

NM_001178078
NM_001178079
NM_001178080
NM_001178081
NM_003153

NM_009284

NP_001171549
NP_001171550
NP_001171551
NP_001171552
NP_003144

NP_033310.2
NP_033310

...
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