SPRY1

SPRY1

Identifiers

SPRY1, hsprouty RTK signaling antagonist 1

External IDs

MGI: 1345139 HomoloGene: 4266 GeneCards: SPRY1

Gene ontology
Molecular function	• protein binding
Cellular component	• Golgi apparatus • membrane • plasma membrane • nucleoplasm • cytoplasm • cytosol
Biological process	• ureteric bud development • negative regulation of neurotrophin TRK receptor signaling pathway • negative regulation of epidermal growth factor receptor signaling pathway • organ induction • bud elongation involved in lung branching • negative regulation of Ras protein signal transduction • multicellular organism development • negative regulation of fibroblast growth factor receptor signaling pathway • negative regulation of GTPase activity • regulation of signal transduction • negative regulation of MAP kinase activity • establishment of mitotic spindle orientation • metanephros development • negative regulation of cell proliferation • negative regulation of ERK1 and ERK2 cascade • epithelial to mesenchymal transition involved in cardiac fibroblast development
Sources:Amigo / QuickGO

RNA expression pattern

PBB GE SPRY1 212558 at fs.png

More reference expression data

Orthologs

Species

Human

Mouse


10252


24063


ENSG00000164056


ENSMUSG00000037211


O43609


Q9QXV9

RefSeq (mRNA)


NM_001258038 NM_001258039 NM_005841 NM_199327


NM_011896 NM_001305440 NM_001305441 NM_001305442

RefSeq (protein)


NP_001244967 NP_001244968 NP_005832 NP_955359

NP_001292369.1 NP_001292370.1 NP_001292371.1 NP_036026.1 NP_001292369
NP_001292370 NP_001292371 NP_036026

Location (UCSC)

Chr 4: 123.4 – 123.4 Mb

Chr 3: 37.64 – 37.64 Mb

PubMed search

ENSG00000164056

ENSMUSG00000037211

NM_001258038
NM_001258039
NM_005841
NM_199327

NM_011896
NM_001305440
NM_001305441
NM_001305442

NP_001244967
NP_001244968
NP_005832
NP_955359

NP_001292370
NP_001292371
NP_036026

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Wikipedia

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