SPHK2

SPHK2

Identifiers

SPHK2, SK 2, SK-2, SPK 2, SPK-2, sphingosine kinase 2

External IDs

MGI: 1861380 HomoloGene: 32456 GeneCards: SPHK2

Gene location (Human)

Chr.	Chromosome 19 (human)

Band	19q13.33	Start	48,619,291 bp
Band	19q13.33	End	48,630,717 bp

Gene location (Mouse)

Chr.	Chromosome 7 (mouse)

Band	n/a	Start	45,709,467 bp
Band	n/a	End	45,718,002 bp

Gene ontology
Molecular function	• sphingosine-1-phosphate receptor activity • transferase activity • nucleotide binding • Ras GTPase binding • kinase activity • protein binding • ATP binding • D-erythro-sphingosine kinase activity • sphinganine kinase activity • NAD+ kinase activity
Cellular component	• cytoplasm • lysosome • membrane • lysosomal membrane • cytosol • intracellular membrane-bounded organelle
Biological process	• phosphorylation • sphinganine-1-phosphate biosynthetic process • female pregnancy • sphingosine metabolic process • sphingosine biosynthetic process • negative regulation of apoptotic process • sphingolipid biosynthetic process • brain development • blood vessel development • positive regulation of cell proliferation • cell proliferation • lipid phosphorylation • sphingosine-1-phosphate signaling pathway • metabolic process
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse


56848


56632


ENSG00000063176


ENSMUSG00000057342


Q9NRA0


Q9JIA7

RefSeq (mRNA)


NM_001204158 NM_001204159 NM_001204160 NM_001243876 NM_020126


NM_001172561 NM_020011 NM_203280

RefSeq (protein)


NP_001191087 NP_001191088 NP_001191089 NP_001230805 NP_064511


NP_001166032 NP_064395 NP_975009

Location (UCSC)

Chr 19: 48.62 – 48.63 Mb

Chr 19: 45.71 – 45.72 Mb

PubMed search

ENSG00000063176

ENSMUSG00000057342

NM_001204158
NM_001204159
NM_001204160
NM_001243876
NM_020126

NM_001172561
NM_020011
NM_203280

NP_001191087
NP_001191088
NP_001191089
NP_001230805
NP_064511

NP_001166032
NP_064395
NP_975009

...
Wikipedia

...