SP110

SP110
Available structures PDB Human UniProt search: PDBe RCSB List of PDB id codes 1UFN
Identifiers
Aliases	SP110, IFI41, IFI75, IPR1, VODI, SP110 nuclear body protein
External IDs	MGI: 3783243 HomoloGene: 82192 GeneCards: SP110
Gene ontology Molecular function • signal transducer activity • metal ion binding • DNA binding Cellular component • nucleus Biological process • regulation of transcription, DNA-templated • GO:0006350 transcription, DNA-templated • viral process • signal transduction Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	3431	101056250
Ensembl	n/a	n/a
UniProt	Q9HB58	n/a
RefSeq (mRNA)	NM_001185015 NM_004509 NM_004510 NM_080424	n/a
RefSeq (protein)	NP_001171944 NP_004500 NP_004501 NP_536349	n/a
Location (UCSC)	Chr 2: 230.18 – 230.22 Mb	n/a
PubMed search

1UFN

3431

101056250

n/a

n/a

Q9HB58

n/a

NM_001185015
NM_004509
NM_004510
NM_080424

n/a

NP_001171944
NP_004500
NP_004501
NP_536349

n/a

SP110 nuclear body protein is a protein that in humans is encoded by the SP110 gene.

The nuclear body is a multiprotein complex that may have a role in the regulation of gene transcription. This gene is a member of the SP100/SP140 family of nuclear body proteins and encodes a leukocyte-specific nuclear body component. The protein can function as an activator of gene transcription and may serve as a nuclear hormone receptor coactivator. In addition, it has been suggested that the protein may play a role in ribosome biogenesis and in the induction of myeloid cell differentiation. Alternative splicing has been observed for this gene and three transcript variants, encoding distinct isoforms, have been identified.

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Wikipedia