SNX26

ARHGAP33
Identifiers
Aliases	ARHGAP33, NOMA-GAP, SNX26, TCGAP, Rho GTPase activating protein 33
External IDs	MGI: 2673998 HomoloGene: 76448 GeneCards: ARHGAP33
Gene location (Human) Chr. Chromosome 19 (human) Band No data available Start 35,774,532 bp End 35,788,822 bp
Gene location (Mouse) Chr. Chromosome 7 (mouse) Band No data available Start 30,522,226 bp End 30,535,060 bp
Gene ontology Molecular function • phosphatidylinositol binding • protein binding • GTPase activator activity • protein kinase binding Cellular component • cytosol • cytoplasm • plasma membrane • cell cortex • actin cytoskeleton • protein complex Biological process • regulation of small GTPase mediated signal transduction • protein transport • positive regulation of GTPase activity • signal transduction • small GTPase mediated signal transduction • transport Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	115703	233071
Ensembl	ENSG00000004777	ENSMUSG00000036882
UniProt	O14559	Q80YF9
RefSeq (mRNA)	NM_001172630 NM_052948	NM_001289670 NM_001289682 NM_178252
RefSeq (protein)	NP_001166101 NP_443180	NP_001276599 NP_001276611 NP_839983
Location (UCSC)	Chr 19: 35.77 – 35.79 Mb	Chr 19: 30.52 – 30.54 Mb
PubMed search

115703

233071

ENSG00000004777

ENSMUSG00000036882

O14559

Q80YF9

NM_001172630
NM_052948

NM_001289670
NM_001289682
NM_178252

NP_001166101
NP_443180

NP_001276599
NP_001276611
NP_839983

TC10/CDC42 GTPase-activating protein is an enzyme that in humans is encoded by the SNX26 gene.

This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. The specific function of this protein has not been elucidated. Alternative splice variants have been described but their full length nature has not been determined.

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