SNRPB2

SNRPB2
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1A9N
Identifiers
Aliases	SNRPB2, Msl1, U2B, small nuclear ribonucleoprotein polypeptide B2
External IDs	MGI: 104805 HomoloGene: 37728 GeneCards: SNRPB2
Gene ontology Molecular function • nucleic acid binding • snRNA stem-loop binding • protein binding • RNA binding • snRNP binding • U1 snRNA binding Cellular component • catalytic step 2 spliceosome • spliceosomal complex • intracellular ribonucleoprotein complex • nucleus • U2 snRNP • small nuclear ribonucleoprotein complex • fibrillar center • nucleoplasm • nuclear speck • U1 snRNP Biological process • mRNA splicing, via spliceosome • mRNA processing • RNA splicing Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	6629	20639
Ensembl	ENSG00000125870	ENSMUSG00000008333
UniProt	P08579	Q9CQI7
RefSeq (mRNA)	NM_198220 NM_003092	NM_021335
RefSeq (protein)	NP_003083 NP_937863	NP_067310.1 NP_067310
Location (UCSC)	Chr 20: 16.73 – 16.74 Mb	Chr 2: 143.06 – 143.07 Mb
PubMed search

1A9N

6629

20639

ENSG00000125870

ENSMUSG00000008333

P08579

Q9CQI7

NM_198220
NM_003092

NM_021335

NP_003083
NP_937863

NP_067310.1
NP_067310

U2 small nuclear ribonucleoprotein B is a protein that in humans is encoded by the SNRPB2 gene.

The protein encoded by this gene associates with stem loop IV of U2 small nuclear ribonucleoprotein (U2 snRNP) in the presence of snRNP-A'. The encoded protein may play a role in pre-mRNA splicing. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. Two transcript variants encoding the same protein have been found for this gene.

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