SMARCA2

SMARCA2
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2DAT, 5DKC, 4QY4
Identifiers
Aliases	SMARCA2, BAF190, BRM, NCBRS, SNF2, SNF2L2, SNF2LA, SWI2, Sth1p, hBRM, hSNF2a, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
External IDs	MGI: 99603 HomoloGene: 2308 GeneCards: SMARCA2
Gene ontology Molecular function • nucleotide binding • RNA polymerase II transcription coactivator activity • DNA binding • DNA-dependent ATPase activity • helicase activity • transcription coactivator activity • histone binding • chromatin binding • hydrolase activity, acting on acid anhydrides • protein binding • transcription regulatory region DNA binding • hydrolase activity • ATP binding • ATPase activity Cellular component • nBAF complex • intracellular membrane-bounded organelle • nucleoplasm • npBAF complex • nuclear chromatin • intermediate filament cytoskeleton • nucleus • SWI/SNF complex Biological process • chromatin remodeling • regulation of transcription, DNA-templated • regulation of transcription from RNA polymerase II promoter • negative regulation of transcription from RNA polymerase II promoter • transcription, DNA-templated • nervous system development • positive regulation of transcription, DNA-templated • negative regulation of cell growth • spermatid development • negative regulation of transcription, DNA-templated • positive regulation of transcription from RNA polymerase II promoter • negative regulation of cell proliferation Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	6595	67155
Ensembl	ENSG00000080503	ENSMUSG00000024921
UniProt	P51531	Q6DIC0
RefSeq (mRNA)	NM_139045 NM_001289396 NM_001289397 NM_001289398 NM_001289399 NM_001289400 NM_003070	NM_011416 NM_026003 NM_001347439
RefSeq (protein)	NP_001276325 NP_001276326 NP_001276327 NP_001276328 NP_001276329 NP_003061 NP_620614	NP_035546.2 NP_001334368 NP_035546 NP_080279
Location (UCSC)	Chr 9: 1.98 – 2.19 Mb	Chr 19: 26.61 – 26.78 Mb
PubMed search

2DAT, 5DKC, 4QY4

6595

67155

ENSG00000080503

ENSMUSG00000024921

P51531

Q6DIC0

NM_001289400
NM_003070

NM_011416
NM_026003
NM_001347439

NP_003061
NP_620614

NP_035546.2
NP_001334368
NP_035546
NP_080279

Probable global transcription activator SNF2L2 is a protein that in humans is encoded by the SMARCA2 gene.

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