SLC39A6

SLC39A6
Identifiers
Aliases	SLC39A6, LIV-1, ZIP6, solute carrier family 39 member 6
External IDs	MGI: 2147279 HomoloGene: 8199 GeneCards: SLC39A6
Gene location (Human) Chr. Chromosome 18 (human) Band 18q12.2 Start 36,108,532 bp End 36,129,385 bp
Gene location (Mouse) Chr. Chromosome 18 (mouse) Band 18|18 A2 Start 24,579,881 bp End 24,603,817 bp
RNA expression pattern More reference expression data
Gene ontology Molecular function • metal ion transmembrane transporter activity • zinc ion transmembrane transporter activity Cellular component • integral component of membrane • cell surface • plasma membrane • integral component of plasma membrane • lamellipodium membrane • endoplasmic reticulum • membrane Biological process • metal ion transport • zinc II ion transmembrane transport • zinc II ion transport • zinc II ion transmembrane import • ion transport • cellular zinc ion homeostasis • transmembrane transport • transport Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	25800	106957
Ensembl	ENSG00000141424	ENSMUSG00000024270
UniProt	Q13433	Q8C145
RefSeq (mRNA)	NM_001099406 NM_012319	NM_139143
RefSeq (protein)	NP_001092876 NP_036451	NP_631882
Location (UCSC)	Chr 18: 36.11 – 36.13 Mb	Chr 18: 24.58 – 24.6 Mb
PubMed search

25800

106957

ENSG00000141424

ENSMUSG00000024270

Q13433

Q8C145

NM_001099406
NM_012319

NM_139143

NP_001092876
NP_036451

NP_631882

Zinc transporter ZIP6 is a protein that in humans is encoded by the SLC39A6 gene.

Zinc is an essential cofactor for hundreds of enzymes. It is involved in protein, nucleic acid, carbohydrate, and lipid metabolism, as well as in the control of gene transcription, growth, development, and differentiation. SLC39A6 belongs to a subfamily of proteins that show structural characteristics of zinc transporters (Taylor and Nicholson, 2003).[supplied by OMIM]

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Wikipedia